-
Jessup M.
Aldosterone Blockade and Heart Failure. N Engl J Med.
2003; 348: 1380-1382.
-
Nabel EG.
Cardiovascular disease. N Engl J Med 2003; 349:
60-72.
-
Weber KT.
Aldosterone and spironolactone in heart failure. N
Engl J Med 1999; 341:753-755
-
Lifton RP,
Dluhy RG, Powers M, et al. A chimaeric 11 beta-hydroxylase/aldosterone
synthase gene causes glucocorticoid-remediable
aldosteronism and human hypertension. Nature 1992;
355: 262-265.
-
Lifton RP,
Dluhy RG, Powers M, et al. Hereditary hypertension
caused by chimaeric gene duplications and ectopic
expression of aldosterone synthase. Nat Genet 1992;
2: 66-74
-
Mitsuuchi
Y, Kawamoto T, Naiki Y, et al. Congenitally
defective aldosterone biosynthesis in humans: the
involvement of point mutations of the P-450C18 gene
(CYP11B2) in CMO II deficient patients. Biochem
Biophys Res Commun 1992; 182: 974-979. Erratum,
Biochem Biophys Res Commun 1992; 184: 1529-30
-
Luft FC.
Present status of genetic mechanisms in
hypertension. Med Clin N Am 2004; 88: 1-18.
-
Wilson FH,
Disse-Nicodeme S, Choate KA, et al. Human
hypertension caused by mutations in WNK kinases.
Science 2001; 293: 1107-1112.
-
Shimkets
RA, Warnock DG, Bositis CM, et al. Liddle's
syndrome: heritable human hypertension caused by
mutations in the beta subunit of the epithelial
sodium channel. Cell 1994; 79: 407-414.
-
Simon DB,
Nelson-Williams C, Bia MJ, et al. Gitelman's variant
of Bartter's syndrome, inherited hypokalaemic
alkalosis, is caused by mutations in the thiazide-sensitive
Na-Cl cotransporter. Nat Genet 1996; 12: 24-30.
-
Simon DB,
Karet FE, Hamdan JM, DiPietro A, Sanjad SA, Lifton
RP. Bartter's syndrome, hypokalaemic alkalosis with
hypercalciuria, is caused by mutations in the
Na-K-2Cl cotransporter NKCC2. Nat Genet 1996; 13:
183-188.
-
Struthers
AD. Impact of aldosterone on vascular
pathophysiology. Congest Heart Fail 2002; 8: 18-22.
-
Stier CT
Jr, Rocha R, Chander PN. Effect of aldosterone and
MR blockade on the brain and the kidney. Heart Fail
Rev. 2005; 10(1): 53-62.
-
Frishman
WH, Stier CT Jr. Aldosterone and aldosterone
antagonism in systemic hypertension. Curr Hypertens
Rep. 2004; 6 (3):195-200.
-
Takeda Y.
Pleiotropic actions of aldosterone and the effects
of eplerenone, a selective mineralocorticoid
receptor antagonist. Hypertens Res. 2004; 27(11):
781-9.
-
Rajagopalan S, Pitt B. Aldosterone antagonists in
the treatment of hypertension and target organ
damage. Curr Hypertens Rep. 2001; 3(3): 240-8.
-
Callera
GE, Montezano AC, Yogi A, Tostes RC, He Y, Schiffrin
EL, Touyz RM. c-Src-dependent nongenomic signaling
responses to aldosterone are increased in vascular
myocytes from spontaneously hypertensive rats.
Hypertension. 2005; 46(4): 1032-8.
-
Brown NJ..
Aldosterone and end-organ damage. Curr Opin Nephrol
Hypertens. 2005; 14(3): 235-41.
-
Stowasser
M. New perspectives on the role of aldosterone
excess in cardiovascular disease. Clin Exp Pharmacol
Physiol. 2001; 28(10): 783-91.
-
Schmidt
BM, Schmieder RE. Aldosterone-induced cardiac damage:
focus on blood pressure independent effects. Am J
Hypertens. 2003; 16(1): 80-6.
-
Weber KT.
Aldosterone in congestive heart failure. N Engl J
Med 2001; 345: 1689-1697.
-
McMurray
J, Pfeffer MA. New therapeutic options in congestive
heart failure. Circulation 2002; 105: 2099-2106.
-
Pitt B,
Remme W, Zannad F, et al. Eplerenone, a selective
aldosterone blocker, in patients with left
ventricular dysfunction after myocardial infarction.
N Engl J Med 2003; 348: 1309-1321.
-
Conlin PR.
Interactions of high salt intake and the response of
the cardiovascular system to aldosterone. Cardiol
Rev. 2005; 13(3): 118-24.
-
Hunt SA,
Baker DW, Chin MH, et al. ACC/AHA guidelines for the
evaluation and management of chronic heart failure
in the adult: executive summary: a report of the
American College of Cardiology/American Heart
Association Task Force on Practice Guidelines
(Committee to revise the 1995 Guidelines for the
Evaluation and Management of Heart Failure). J Am
Coll Cardiol 2001; 38: 2101-2113.
-
Liew D,
Krum H. Aldosterone receptor antagonists for
hypertension: what do they offer? Drugs 2003;
63(19): 1963-72.
-
Sierra C,
Ruilope LM. Role of the selective aldosterone
receptor blockers in arterial hypertension. J Renin
Angiotensin Aldosterone Syst. 2004; 5(1): 23-5.
-
Ambroisine
ML, Milliez P, Nehme J, Pasquier AL, De Angelis N,
Mansier P, Swynghedauw B, Delcayre C. Aldosterone
and anti-aldosterone effects in cardiovascular
diseases and diabetic nephropathy. Diabetes Metab.
2004; 30(4): 311-8.
-
Reyes AJ,
Leary WP, Crippa G, Maranhao MF, Hernández Hernández
R. The aldosterone antagonist and facultative
diuretic eplerenone: a critical review. Eur J Intern
Med. 2005; 16(1): 3-11.
-
Brennan
BJ, Martin NE. Eplerenone: selective aldosterone
antagonism in management of cardiovascular and renal
disease. J Am Pharm Assoc (Wash DC). 2004;
44(5):604-10.
-
Gumieniak
O, Williams GH. Mineralocorticoid receptor
antagonists and hypertension: is there a rationale?
Curr Hypertens Rep. 2004; 6(4): 279-87.